Sentence examples for mainly repaired through from inspiring English sources

In mammalian cells, nuclease-mediated DNA double strand break is mainly repaired through the error-prone non-homologous end-joining (NHEJ) repair pathway, eventually leading to accumulation of small deletions or insertions (indels) that can inactivate gene function.

4NQO is known to induce lesions that are mainly repaired through the nucleotide excision repair (NER) pathway, exclusive of hOGG1.

These lesions are mainly repaired through nucleotide excision-repair, a mechanism not yet established in the mitochondria.

DSBs are mainly repaired through the mutagenic nonhomologous end joining (NHEJ) repair pathway, leading to disruption of the targeted gene [ 10].

In our previous studies, we demonstrated that CNDAC-induced SSBs can be repaired by the transcription-coupled nucleotide excision repair pathway, whereas lethal DSBs are mainly repaired through homologous recombination.

Bulky nucleotide adducts in UV-damaged DNA are mainly repaired by the nucleotide excision repair (NER) system.

The 8-OHdG adduct is mainly repaired by base excision repair (BER) mechanism of the cell [ 37, 38].

In higher eukaryotes, DSBs are mainly repaired by homologous recombination (HR; error-free repair) and non-homologous end-joining (NHEJ; error-prone repair).

Additionally, these adducts are mainly repaired by the NER pathway (Park et al, 2001).

DSBs are mainly repaired by either HR [ 80] or NHEJ [ 81].

In bacteria, replication fork arrest is mainly repaired by homologous recombination [ 1].