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By consulting the Connectivity Map, a database of drug-associated gene expression profiles [13], [14], we identified molecules that induced gene expression changes after cell treatment that were mainly opposite to those induced by infection.
Mas-R is an important member of the local tissue RAS, acting mainly opposite to the well-known AT1-R.
Mas-receptor (Mas-R) is a potential receptor acting mainly opposite to the well-known angiotensin II receptor type 1.
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The local, short time range variations of estimated flow shown in Figure 6A constitute an example of motion which is mainly in opposite direction with respect to the average stream, dictated by the pressure distribution (Figure 5A) and in agreement with the local flow estimated on a long time range (Figure 6C).
Mainly, the opposite is true.
Each cerebral hemisphere contains a map that controls mainly the opposite side of the body.
The addition of superabsorbent polymer (SAP) mainly has two opposite effects on the pore structure of ultra-high performance concrete (UHPC): the densification of microstructure due to internal curing (IC) and the increase of large voids by swollen SAP particles.
The correlated residues are within van der Waals contact and appear to maintain the active site architecture; the anti-correlated residues are mainly distributed on opposite sides of the catalytic cavity and coordinate the motions likely required for the substrate entry and product release.
Based on this analysis, we identify two main clusters (I. and II)., distinguished mainly through the opposite regulation of H2AK5, H4K16ac, as well as H4K12ac (Fig. 8A, top 4 rows).
The Moroccan port of Al-Hoceïma, founded by Spaniards in 1926 as Villa Sanjurjo, on the mainland opposite, is mainly a fishing port.
The opposite approach mainly promotes the formation of linear grafted oligomeric structures.
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