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It consists mainly of cells that line the walls of capillaries in the brain and are so tightly packed that many molecules in the bloodstream cannot slip out between cells to reach the brain tissue itself.
Cultured HMECs are composed mainly of cells from the basal breast epithelial layer.
The resulting tumors are composed mainly of cells expressing ductal progenitor markers and possess functional features of cancer stem cells.
The Arabidopsis IRX10 and Populus PtGT47A-1 genes are expressed within the vascular tissue made up mainly of cells rich in secondary cell walls.
Clinically, basal-like breast cancer is characterized as the triple-negative phenotype (ER, PR, HER2, all negative) and as resembling stem-like cells, composed mainly of cells expressing the cancer stem cell markers CD44+ and cytokeratin 5/6 [ 31- 33].
Our results demonstrate that in these mice, hepatocyte death initially leads to the activation of ductal progenitors and inflammation, followed by spontaneous development of hepatocellular carcinoma comprised mainly of cells featuring cancer stem cell properties.
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Time-lapse imaging of HUVECs cultured on Matrigel revealed minimal cell migration or proliferation, with TLS formation consisting mainly of cell stretching to facilitate connection between adjacent cells.
CARS imaging of content-rich cell poles which include cell membrane and lipid droplets and of content-poor cell poles which consist mainly of cell membrane yielded strong and weak CARS contrast, respectively (Fig. 6E).
> Table 1 shows central regulators of the cell comprising regulation mainly of cell cycle [MYC, E2F, STATs, RELB (NFKB), JUN, p53, CEBBA], but also apoptosis [p53, RELB (NFKB), differentiation (EGR1), immune response (CEBBP) and metabolism (HIF1A)].
The mouse spleen is composed mainly of T cells, B cells and erythrocytes in addition to smaller numbers of myeloid cells.
In this scenario, anergy of regulatory T cells, mainly of Th2 cells mediating protection from autoimmune diseases [ 81], is postulated.
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Justyna Jupowicz-Kozak
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