Sentence examples for mainly mediated through from inspiring English sources

On the other hand, a recent report suggests that in melanoma cells, CXCL-8-mediated chemotaxis is mainly mediated through CXCR1 (Ramjeesingh et al, 2003).

We recently showed that the effect of myoblast sheets can be further enhanced by gene therapy, and that after MI, in both acute and chronic HF their therapeutic effect is mainly mediated through production of paracrine mediators [9], [10].

The binding of PmLec to lipopolysaccharide was mainly mediated through the O-antigen.

This suggests that the impact of BE is mainly mediated through pedestrian activity.

Their angiogenic effects are mainly mediated through VEGF receptor 2 (VEGFR2).

As results, retionid-induced inflammation was mainly mediated through MCP-1 and IL-8 as evidenced by increased levels of mRNA expression and protein secretion.

The results of Western blotting demonstrated that the anti-cytokine potential of compound 7l is mainly mediated through the inhibition of p38 MAPK signaling pathway.

Based on our current study, we propose a potential model where negative regulation of p16 is mainly mediated by SIRT1 through epigenetic and genetic mechanisms during CR (Fig. 8).

It is known that cellular senescence induced by oncogenic Ras is mainly mediated by excessive signalling through the ERK signalling pathway[19], [20], [21].

The plasma glucose lowering action of rhodiola-water extract is mainly mediated by β-endorphin release through an activation of opioid μ-receptors to achieve the higher of GLUT 4 gene expression and/or the decrease of hepatic PEPCK gene expression.

The intrinsic pathway of apoptotic cell death is mainly mediated by the BCL-2-associated BCL-2-associated BCL-2-associated Xation of the mitochondrial outer memBAXne (MOM) and the concomitant release of cytochrome c into the cytosol.