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Filipin analysis of kidneys from the chronic CD treatment study revealed no obvious differences between treated and untreated Npc1−/− mice, even though CD is thought to be excreted mainly intact in urine [23] (Fig. S2A).
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Thus, the crude mitochondrial fraction contained mainly intact mitochondria (90%), in which the mtDNA was protected inside intact outer and inner membranes (Table 1).
The historic old town is walled in and mainly intact, representing some of the finest architecture from Spanish Colonial rule.
Indeed, mainly intact circular OvHV-2 genomes have been found in T-lymphocytes derived from cattle with MCF, which speaks for a dominating latent infection.
So when measuring the enzyme activities in the isolated mitochondria this represents mainly intact subsarcolemmal mitochondria.
Even at high temperatures, ECD spectra of LmCld show mainly intact secondary structural elements that differ from very uncommon minima of SaCld in the far UV region [10].
In a CNV lesion, the overlying neuronal outer nuclear layer is mainly intact.
Mice treated with 25 mg/kg LAQ showed mainly intact myelin compared to moderate demyelination with 5 mg/kg LAQ and almost complete demyelination in untreated controls.
The route has remained mainly intact since its assignment.
The high CCO latency in both homogenate and crude mitochondria indicates that the outer membrane was mainly intact [ 14, 15].
A typical gradient with three distinct bands is shown in figure 2 A. Intact cells were found to pellet to the bottom of the gradient (data not shown) and "fraction 3" also comprised mainly intact cells (fig. 2 B).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com