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The phrase 'mainly determined' is correct and usable in written English.
It is an adverb phrase that is used to indicate that something is primarily decided or controlled by a particular factor or factors. For example: "The length of the lunch break was mainly determined by the number of tasks that needed to be completed each day."
Exact(60)
He came to Oxford mainly determined to understand black Jamaica.
This is mainly determined by the second variable: what's the donor getting in return?
The specificity of the intracellular signals is mainly determined by BMPRI.
This indicates that the TH index was not mainly determined by the number of mutations.
Initial droplets velocity is mainly determined by input power.
Caloric intake was mainly determined by dietary fat.
In such cases, the profile is mainly determined during impregnation.
Price mattered, but it mainly determined whether people would buy an item, rather than where they would buy it.
The quantity of seeds planted, or rate of planting, is mainly determined by the characteristics of the vegetable plant.
The yield of a crop is mainly determined by the seed's intrinsic properties, not the inserted genes.
Hence, the decreasing of the formation energy of SbTe is mainly determined by the effect of lattice parameters changes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com