Together with the immunohistochemical data, which indicated that macrophages mainly cluster with cells expressing biochemical EMT markers locally in the tumor, we conclude that the levels of active β-catenin in F9-tumors were too low to be detected by western blotting.
Within this giant component, 47% of drugs were nervous system acting (red nodes in Figure 1 and Supplementary Table S2) and were mainly clustered, with an average number of neighbors of 10.6 compared with 4.3 (including the nervous system drugs) for the whole network, indicating an important number of shared targets.
There were some exceptions in which subtractive effects were observed, mainly clustered within subjects with diabetes and co-existing heart disease (physical functioning, role-physical, social functioning and role-emotional scales) or musculoskeletal illnesses (bodily pain and social functioning scales).
Mutations that segregate with PD are mainly clustered within the catalytic core, suggesting that alteration of the enzymatic functions may be correlated with pathology.
There are mainly two clusters with a high potential for using e-carsharing schemes: 'innovative technology-loving multioptionals' and 'ecological PT- and bike-lovers'.
Although an ex vivo analysis with the anti-CA IX antiserum yields a pattern with uniform staining intensity, the regions targeted in vivo by SIP A3) mainly cluster around central vascular structures, with a gradient of staining intensity (green) which reflects a gradient in antibody diffusion.
General reaching-related activity compared with fixation mainly clustered in the left hemisphere (Fig. 2 a ), spanning from motor cortex over somatosensory cortex to the PPC.
In four patients (one with Type IIa and three with Type IIb), the laminar structure was less severely affected, with fewer DNs mainly clustered in particular cortical layers.
The genetic map revealed that there were mainly two distinct clusters with one cluster dominated by poultry stains (81.6% among a total of 49) between 2003 and 2006, and the other cluster dominated by wild-bird strains (40.7% among a total of 27) between 2007 and 2008.
For example, the largest cluster M5 cluster mainly overlapped with the cluster K3 (Fig. S5-A), therefore confirming the misregulation of genes in irradiated atm.
