Sentence examples for mainly been indicated from inspiring English sources

Surgical application of the saddle has mainly been indicated in older patients, or in difficult resections where the long operative time can increase intraoperative complications such as hemorrhage or cardiac problems.

As a consequence, elective THR and TKR procedures have until relatively recently been indicated mainly in older patients, but even prostheses which make use of the latest technological developments (eg, unicondylar knee prostheses) are not yet routinely recommended for use in younger patients.

Meanwhile, MSC administration could also decrease the activities of matrix metalloproteinase-2 (MMP-2), a collagenase mainly produced by myofibroblasts that have been indicated to have a role in liver fibrosis; however, we did not find much change in matrix metalloproteinase-9 (MMP-9) (Supplementary Figure 4).

It is indicated mainly on the study of two pathologies: venous thrombosis and venous insufficiency.

Intubation was indicated mainly for urgent surgery (42%) or acute respiratory failure (35%).

The treating surgeons had not considered that revision was indicated, mainly because the patients did not suffer severe pain or any pain at all.

Thus, microsurgery is indicated mainly in case of large tumors and deterioration of useful hearing during observation with attempt at its preservation and in case of disabling symptoms (mainly vertigo) [ 1, 3].

This procedure is indicated mainly in secondary rhinoplasty when the cartilages of the tip are completely destroyed, and in primary rhinoplasty when the tip is excessively wide and bulbous.

In this trial, ultrasonography and MRI were indicated mainly in the management of patients with Crohn's disease, in case of high fistulae with transphincteric, extrasphincteric, suprasphincteric and/or multiple tracks, recto-vaginal fistulae, often associated to proctitis.

Microsurgery is indicated mainly in the case of large tumors, the deterioration of useful hearing during observation with attempt for its preservation, and in the case of disabling symptoms [ 2, 3].

The determination of serum bFGF represents a simple, inexpensive and noninvasive approach, also when compared with recently proposed nipple aspiration [ 27], and would seem to be indicated mainly for women older than 70 years of age to whom mammograms and clinical screening are not routinely offered.