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Given the strong effect on sensorimotor gating and deficits in social behavior, MIA in animal models has mainly been associated with a schizophrenia-like phenotype (Meyer et al. 2005) or autism-related characteristics (Fernández de Cossío et al. 2017).

Many viruses and viral proteins affect the PI3-kinase-Akt signaling pathway, and this has mainly been associated with its fundamental role in the regulation of apoptosis and cellular survival [50].

It should be noted that the studies we mentioned above addressed potential BALT persistence in viral infection, while in the case of bacteria lymphoid structures have mainly been associated with chronic disease, as in the case of M. tuberculosis and P. aeruginosa [30], [32].

Until recently apoptosis, or programmed cell death, has mainly been associated with the elimination of unwanted or overproduced cells.

Rifampicin resistance has mainly been associated with mutations in a limited region of the rpoB gene (Telenti 1993).

Benzene, an important component of petrol, is a widely distributed environmental contaminant [ 11] and has mainly been associated with increased incidence of blood disorders [ 12].

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Therefore, the results indicated that CF-HT exerted more potent hypolipidemic activity and definite hepatoprotective effect which may mainly be associated with its antioxidative property in mice.

While the lower alpha band was proposed to be involved in attention, the upper alpha band mainly was associated with working memory.

Finally, some genes were expressed with similar profiles following activation by either PAR1 or PAR2, these mainly being associated with tumorigenesis and cancer progression, implicating a possible sharing of proliferative mechanisms between these two receptors on cell surfaces.

This indicated that epigenetic silencing of ESR2 appearing in 90% of CRC cases could mainly be associated with carcinogenesis in the proximal colon [ 39].

Its function mainly has been associated with transcriptional regulation (Jones 2012).

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