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Discover LudwigThe phrase 'mainly affects' is correct and usable in written English.
You can use it when you need to describe how a particular thing primarily impacts another thing. For example, "The recent economic downturn has mainly affected lower-income families."
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It mainly affects boys.
Howard's injury mainly affects his kicking.
Unfortunately malaria doesn't pack much political punch as it mainly affects the poor and disenfranchised.
"It mainly affects poor farmers living in remote rural villages," he said.
Asperger's, a high-functioning form of autism, mainly affects people's social interaction and communication skills.
The illness mainly affects the elderly, very young children and people with weakened immune systems.
As a disease, trachoma mainly affects the most vulnerable members of neglected communities – women and children.
Four were under five, underlining's H1N1 dominance of this flu season since it mainly affects other groups than the elderly.
The parasite is transmitted through sand flies, and mainly affects children whose immune systems are compromised.
That if a deplorable practice mainly affects Asian immigrants, it's not really worth criminalizing?
So the ban mainly affects the contractors carrying out billions of dollars in development projects.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com