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The main weaknesses include different methods used to quantify sperm count; the paucity of studies that have examined TCDD effects on DSP and the ambiguous nature of those results; the absence of documented changes in testicular and spermatozoa morphology; and the divergence of effects of TCDD upon sperm counts and circulating androgen levels.
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Main weaknesses identified included linguistics ambiguity; unclear planning hierarchy; lack of clear time-frames; and adoption of highly ambitious plans.
These weaknesses include both experimental issues and also the relative lack of mechanism (which is why the main phenomena have to be addressed experimentally).
My biggest weaknesses include..."...
Potential weaknesses include effects of population admixture and multiple comparisons.
Weaknesses include limited anonymity for the preceptors.
Other weaknesses include the use of subjective measures of sweating.
35 Other weaknesses include residual and unmeasured confounding.
The results of the quality assessment (Table 1) showed that only one of the five randomized clinical trials included demonstrated a high-quality score (25 of 27) [ 25]. > The main weaknesses of the included articles were the lack of information concerning the following three criteria: external validity, description of randomization, and description of the patients lost to follow-up.
The main weaknesses of the studies included were the inaccurate descriptions of the patients and of the interventions studied, and the lack of long-term assessment of the outcome.
The relatively small size of the cohort limited the power of the study, the other main weaknesses being the absence of information on confounders including ethnicity, alcohol consumption, smoking status and environmental exposure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com