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Our results show that distinct clusters exist corresponding to the main tissues of epithelial human cancers.
In the present study we show that visfatin/Nampt is produced by the three main tissues of the human OA joint but to a greater degree by synovium.
Here, we describe the miRNA expression profiles in the main tissues of the eye and show the spatiotemporal distribution of 221 miRNAs.
A gross necropsy was performed focusing on main tissues of disease involvement (spleen, thymus and lymph nodes) and tumor infiltration (liver, kidney, lung, brain).
Typically, these compartments include the main tissues of the body, namely, adipose, bone, brain, gut, heart, kidney, liver, lung, muscle, skin, and spleen.
Here, we demonstrate that the three main tissues of the human OA joint (that is, cartilage, subchondral bone and synovial membrane) store and release visfatin/Nampt, which is more significantly produced by synovial membrane than cartilage and subchondral bone.
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Omentin expression varies throughout the body (heart, lungs, ovary and placenta) but its main tissue of production is now considered to be visceral adipose tissue [ 2, 3].
As shown in Fig. 2a- b, pre-molt samples (stage D) were readily identified by the formation of new setae within the existing ones and invaginations into the main tissue of the cirri.
Since muscle is the main tissue of protein deposition and energy storage, we identified four glycolytic enzyme DEGs in M. nipponense in response to hypoxia, suggesting that these were important regulators in response to hypoxia stress in muscles.
Furthermore, while liver is the main tissue of folate storage and metabolism [ 31], supplementation with methyl donors including folic acid has been shown to affect gene expression and DNA methylation in colon tissue in a mouse model of colitis [ 32], suggesting that colon may be an important target tissue for folate supplementation.
Digestive gland is a main tissue for accumulation of both Cd forms, but changes in antioxidant enzyme activities are smaller than in gills.
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