As shown in Figure 2, three main subgroups were identified.
A strong association between the pretreatment serum beta 2-m level and survival was demonstrated, the data for the 2 main subgroups being very similar.
Importantly, the prognostic impact of the two main subgroups was confirmed in an independent data set from The Cancer Genome Atlas (TCGA), consisting entirely of GBM (Verhaak et al, 2010), whereas that of the six subgroups was confirmed in the REMBRANDT (Madhavan et al, 2009) and Phillips et al (2006) data sets consisting of all seven gliomas.
Genetic analysis of Chinese PRRSV isolates showed that the main subgroup is the North American type.
Classically, two main histological subgroups are defined morphologically, ductal and lobular carcinomas, which together represent 90% of all breast cancers.
bAnalysis for main CNS tumour subgroups are shown in Table 3.
We focused on interactions involving haplotypes with significant main effects, as the biological basis is unclear for interactions involving significant subgroup variation in exposure disease associations with no main effects when subgroups are combined [ 44].
One possibility is that potential parental diploids for the main commercial subgroups were under-represented in the collection, such as demonstrated by the absence of ancestry in diploids groups for some recent tetraploid hybrids developed by FHIA evaluated in this study.
The prevalence, distribution and types of malnutrition observed in the main study groups and subgroups are shown in tables 3– 5. Sixty-six of 73 children with CHD were malnourished with a WAZ score of ≤−2, giving an overall prevalence of malnutrition of 90.4% in cases compared with 21.1% in controls (p=0.0001).
In an English cross-sectional study by Langworthy et al. [ 34], baseline variables on the details of pain obtained from patient files were the starting point for the hierarchical cluster analysis, which revealed 2 main subgroups that were differentiated by constant and fluctuating pain, respectively.
