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We also considered and fit Cox proportional hazards models, using adjudicated time to hip fracture and censored at the end of the main study, death, or last follow up visit.
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The main study outcome was death from any cause at six months following AIDS diagnosis (i.e., these were considered early mortality deaths), and it constituted the focus of this analysis.
In the UKPDS, deaths from cancer were too few for any conclusion to be reached about differences between metformin and conservative management arms (RR 0.71 [95% CI 0.29 1.76]), while in the main study the cancer death rate was identical in the therapy (sulfonylurea or insulin) and conservative arms (RR 0.98 [95% CI 0.64 1.52]) [ 14, 15].
All-cause death and CVD death were the main study outcomes.
The main study outcomes were hospitalization or death from stroke and CAD.
Causes of death in the main study were interpersonal violence (six), suicide (three), injuries from traffic incidents (two), and a range of natural causes (seven), including AIDS (one).
Because of the limited sample of women, who contributed relatively few deaths to the main study, we were unable to perform a meaningful parallel analysis on women.
The main study outcomes were GP episodes, hospitalizations and deaths due to respiratory disease.
Main study.
†Recorded as main cause of death on death certificate in death registry database.
In the past, apoptosis and accidental cell death are the main cell death types that have been widely studied [ 18].
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