Sentence examples for main signalling pathway from inspiring English sources

It has been previously described that the effect of cancer signalling pathways can change due to the mutation or loss of oncogenes outside the main signalling pathway.

Glu (glutamate), the excitatory transmitter at the main signalling pathway in the retina, is critically involved in changes in the protein repertoire through the activation of signalling cascades, which regulate protein synthesis at transcriptional and translational levels.

While the main signalling pathway involves CTR1, it is worth pointing out that subtle effects of ethylene receptor signalling might occur via the two-component system's phosphotransfer proteins and response regulators in Arabidopsis (known as AHPs and ARRs, respectively).

The main signalling pathway downstream of the insulin receptor in GLUT4 translocation involves sequential activation of PI3K (phosphoinositide 3-kinase) and Akt, and subsequent inactivation of AS160 by Akt-mediated phosphorylation.

The two main signalling pathways downstream from the ErbB receptors are the phosphatidylinositol 3'-kinase (PI3K) and the mitogen activated protein kinase (MAPK) [4].

The model incorporated the three main signalling pathways, i.e. IRE1 α, PERK and ATF6, the interconnections between these pathways, and the downstream genetic regulatory interactions.

In spite of conflicting data, the ras/MAPK and cAMP/PKA pathways seem the main signalling pathways involved in the conidial germination of Aspergillus [ 4- 9].

Further network pathway analysis in this disease group suggested that two main signalling pathways, TP53 and TNF, may be involved in NAC nonresponsiveness.

It is no surprise that the main signalling pathways that regulate cell growth, metabolism, senescence and apoptosis under normal conditions also regulate the stress responses.

We have analysed the main signalling pathways of these cell lines and compared them to those of a cell line derived from normal melanocytes.

Among the main signalling pathways implicated in D/V patterning are sonic hedgehog (SHH), wingless (WNT) and the TGFβ-superfamily, mainly through the function of BMPs.