Sentence examples for main signaling pathways from inspiring English sources

The androgen receptor is one of the main signaling pathways that underlies the growth of the prostate and prostate cancer, said Dr. Barbieri, who is a member of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine and a urologic surgeon at NewYork-Presbyterian/Weill Cornell Medical Center.

Fig. 1 Positive and negative effects of GPC3 on its two main signaling pathways.

Table 8 summarizes the main signaling pathways of artemisinin and its derivatives in cancer control.

The model incorporates elements of the main signaling pathways involved in breast cancer: RTK signaling (e.g. IGF1R and HER2/HER3), PI3K signaling (e.g. PI3K and PTEN), MAPK signaling (e.g. RAS and MAPK), AKT signaling (e.g. AKT, PDK1, and FOXO3), mTORC1 signaling (e.g. mTORC1, TSC, and S6K), and ER signaling (e.g. ESR1 and MYC).

Finally, cyclotraxin-B inhibits the two main signaling pathways downstream TrkB with similar amplitude of effects.

VEGFR2 is the receptor that initiates the main signaling pathways activated by VEGF.

Overall, IPA analyses confirmed the result obtained from the GenMAPP/MAPPFinder analysis; namely that insulin signaling is the main signaling pathway altered in both groups (data not shown).

These data suggest that calcium mobilization instead of cAMP is used as the main signaling pathway for orexin receptors from amphibians to mammals.

It has been established that the fibroblast growth factor 4 (FGF4) signaling pathway is the main signaling pathway required for proliferation and self-renewal of TS cells and polar trophectoderm/extraembryonic ectoderm [4]-[7].

uPAR gene is upregulated by the activated RAS signaling pathway, the main signaling pathway activated in colon cancer [ 72].

The main signaling pathway that has been shown to be responsible for AVE specification is the Nodal pathway [ 3].