Sentence examples for main regulatory pathway from inspiring English sources

It is known that the PI3K/AKT signaling is the main regulatory pathway of FOXO3a [ 44, 47, 48].

Many genes of the SREBP2 signaling pathway, the main regulatory pathway of cholesterol biosynthesis, are up-regulated (Mbtps1, Insig1, Insig2), but not Srebp2 itself (Table 3).

Inhibition of MMP transcription prevented invasion in vitro and decreased the colonization of the lung cancer cells in an in vivo tail vein metastasis model [ 9], indicating that transcriptional regulation is the main regulatory pathway controlling the expression of MMPs.

Scheme summarizing the main regulatory pathways involved in proliferation control and organ formation in the pLLP.

Although the IGF-1 pathway is one of the main regulatory pathways in skeletal muscle (Velloso, 2008), little is known about how it is affected by estrogen.

Some of the main regulatory pathways involving iron, inflammation, erythropoiesis, hypoxia, growth factors and hormones have been studied and the mechanisms of regulation deciphered.

Although the DREB1/CBF regulon appeared to be one of the main regulatory pathways involved in cold stress, and multiple low-temperature regulatory pathways in addition to the DREB1/CBF pathway were also studied.

Making primarily use of the fruit fly Drosophila melanogaster, injection or pricking of the cuticle for application of bacteria has been the method of choice that has enabled the identification of the main regulatory pathways of innate immunity [ 18– 22].

The central activating kinase for this pathway is called the NIK (NFκB-inducing kinase), and the degradation of this kinase is the main regulatory step in the pathway [ 21].

Targeting NF-κB is considered important in inhibiting NOS because it is the main regulatory step in the pathway leading to iNOS expression.

The main regulatory enzyme of the MVA pathway is HMGR [ 50].