Sentence examples for main receptor that from inspiring English sources

Although mGluR5 is a major group I mGluR in rat hippocampal neurons [42], [44], mGluR1 is the main receptor that regulates intracellular calcium accumulation in hippocampal neurons [45].

These results suggest that the IGF1R is the main receptor that is mediating downstream promitogenic signaling after insulin analogue stimulation.

Low-density lipoprotein receptor-related protein 5, the main receptor that mediates Wnt signaling, plays a critical role in bone mass regulation.

TLR2 DN, but not TLR4 DN, resulted in inhibition of HBD-2 expression, confirming that TLR2 is the main receptor that mediates NTHi signaling through induction of β-defensin 2 (Fig 5A).

In the 1990s, TLR-4 was found to be the main receptor that binds LPS, leading to the release of TNF-α and IL-1 and activation of numerous downstream intracellular signaling pathways via the NF-κB transcription factor [ 50, 53].

Of these receptors, the killer immunoglobulin-like receptors (KIRs), which interact with human leukocyte antigen (HLA) class I ligands on the surface of target cells, are the main receptors that recognize the presence or absence of antigens on cell surface [ 1, 2].

While AT1 may be the main receptors that mediate the effects of Ang II on blood pressure, AT2 may be also partially involved in blood pressure regulation [ 60].

Apart from GABAB receptors [33], the other main receptor type that is known to be positively coupled to GIRK channels in TC neurons is the adenosine A1 receptor [34].

The level of neuropilin-1, an accessory receptor of VEGF to main receptor corresponds with that of VEGF and ang-1.

A series of betamethasone 17α-carbamates were designed, synthesized, and evaluated for their ability to dissociate the two main functions of the glucocorticoid receptor, that is, transactivation and transrepression, in rat cell lines.

VEGFR2 is the receptor that initiates the main signaling pathways activated by VEGF.