Sentence examples for main receptor of from inspiring English sources

A new class of anti-retrovirals, cyclotriazadisulfonamide (CADA) and its derivatives, specifically down-regulate CD4, the main receptor of HIV, and prevent HIV infection in vitro.

Thus, it could be expected that signaling by the main receptor of another Th1 cytokine like TNF would also be protective against aneurysms.

Our data suggest that SLPI may disrupt the interaction of CD4, the main receptor of HIV-1, at least with the PLSCR1 membrane protein at the cell surface of CD4-expressing cells.

Since it was previously reported that the inhibition of HIV-1 replication by SLPI resulted from a direct action on the virus entry process [9], [11], we asked whether PLSCR1 could directly associate with CD4, the main receptor of HIV-1 at the cell surface of T lymphocytes.

Among a variety of Mtb receptors in the membrane of PMN, CD11b is one of the main receptor of phagocytosis which binds complement factor C3bi, as well as non-opsonized bacteria at a different site from C3bi binding site [ 38].

The described phenotypes show that ecdysone signalling loss of function (by disruption of ecdysone biosynthesis or by expression of EcR and USP dominant-negative forms) and overexpression of the main receptor of the pathway, EcR cause similar abnormalities.

We have also determined the expression of KDR and FLT1, the main receptors of VEGF-A in the arteries [ 20].

Compared to the main receptors of VEGF, NRP-1 function in conjunction with multiple ligands and receptors to guide vascular development remains elusive [ 5, 9].

In the present study, we have investigated all the genes involved in the melatonin pathway by mutation screening of AA-NAT (arylalkylamine N-acetyltransferase), ASMT, MTNR1A, MTNR1B (melatonin receptor 1A and 1B) and GPR50 (G protein-coupled receptor 50), encoding both synthesis enzymes and the three main receptors of melatonin, in 109 patients with autism spectrum disorders (ASD).

Over a long period of time, soil is generally the main receptor for much of the urban contamination, both from diffuse and point sources (Johnson and Demetriades 2011; Mielke et al. 1999).

Next we investigated the possibility of proteolytic removal of the main receptor for VEGF mediated angiogenesis, VEGFR2.