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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
main question regarding
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "main question regarding" is correct and usable in written English.
It can be used when introducing a primary inquiry or topic of discussion related to a specific subject. Example: "The main question regarding the effectiveness of the new policy is whether it will lead to improved employee satisfaction."
✓ Grammatically correct
Science
News & Media
Formal & Business
Alternative expressions(19)
central question of
key question of
central message of
key subjects of
key matters of
key issues of
crucial issues of
main theme of
key takeaway of
crux of the matter
main theme
primary focus of
key aspect of
main point of
main conclusion from
significant aspect of
essence of
driving force behind
underlying principle of
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
1 human-written examples
At the present, the main question regarding the optimal management for localized primary MALT OALs cannot be answered yet, since no prospective randomized trials comparing different upfront treatments have been conducted.
Human-verified similar examples from authoritative sources
Similar Expressions
59 human-written examples
Although there is a wealth of studies investigating retinal and extraretinal SPEM control, the main questions regarding the cortical mechanisms involved in the processing of SPEM to different stimulus velocities are still unresolved.
Science
Although, the initial purpose of the survey was to assess the perception and the expectation of the employers on employability skills, the research also addressed a number of main questions regarding the level of requirement of engineering employability skills according to the needs of their industries.
The current study set off to investigate three main questions regarding the processing of auditorily presented number words.
These results are the first comprehensive analysis of the ubiquilin gene family available and solve the main questions regarding the origin and diversification of this family in eukaryotes.
Science
One of the main questions regarding the endocytic proteins acting in the cell nucleus is the mechanism of their nuclear translocation.
Science
In this review we are going to find answers, based on the best available evidence, for three main questions regarding PDA management: to treat or not to treat? when to treat? and how to treat?
Here we aim to address two main questions regarding the effects of RW inducing conditions on the recalcitrance of SRC willow stem biomass:- 1) Do genotypic differences occur in enzymatic glucose release at the whole tree level in response to controlled RW inducing conditions?
Science
The main question regards which kind of informed consent is necessary for a procedure of irreversible anonymization of samples and data.
Science
Our main questions regard (1) the nature and quantity of parent child communication after paediatric injury and (2) the relation between parent child communication and children's psychological recovery.
Science
In particular, this applies to the main research question regarding differences in the number of days of inpatient care.
Science
Expert writing Tips
Best practice
When using "main question regarding", ensure that the question is indeed the most important or central one to the topic being discussed. Avoid using it for minor or tangential inquiries.
Common error
Avoid using "main question regarding" in informal conversations or casual writing. Opt for simpler alternatives like "the big question is" or "what's important is" for a more natural tone.
Source & Trust
82%
Authority and reliability
4.1/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "main question regarding" functions as an introductory element to highlight a central inquiry or issue. As seen in Ludwig, it commonly introduces the most important question within a discussion or analysis.
Frequent in
Science
52%
News & Media
24%
Formal & Business
12%
Less common in
Wiki
6%
Encyclopedias
3%
Reference
3%
Ludwig's WRAP-UP
In summary, "main question regarding" serves as a robust and versatile phrase to introduce a central inquiry in various contexts. Ludwig AI indicates the phrase is grammatically correct and finds frequent use in scientific, news, and business-related materials, establishing its relevance across diverse fields. When aiming to pinpoint a crucial inquiry, this phrase proves invaluable. Though highly adaptable, it is more suitable for formal writing than for casual conversation. Alternatives such as "primary question concerning", "key question pertaining to", or "central issue concerning" can be employed to fine-tune the specific emphasis. When you choose to use it, make sure the question you are introducing is truly the main one, and consider your audience to ensure it aligns with the tone.
More alternative expressions(10)
Phrases that express similar concepts, ordered by semantic similarity:
primary question concerning
Replaces "main" with "primary" and "regarding" with "concerning", slightly altering the tone.
key question pertaining to
Substitutes "main" with "key" and "regarding" with "pertaining to", giving a more formal feel.
central issue concerning
Replaces "question" with "issue" and "regarding" with "concerning", shifting the focus to a problem.
principal inquiry into
Uses "principal inquiry" instead of "main question", suggesting a more investigative approach.
major point about
Replaces "question regarding" with "point about", simplifying the sentence structure.
chief concern in relation to
Emphasizes the "concern" aspect, adding "in relation to" for context.
fundamental question on the subject of
Uses "fundamental question" for emphasis and adds "on the subject of" for clarity.
core question surrounding
Replaces "main" with "core" and "regarding" with "surrounding", indicating a central question.
primary focus of inquiry into
Highlights the "focus" aspect, framing it as an "inquiry".
critical point with respect to
Replaces "question" with "point" and "regarding" with "with respect to", shifting the emphasis.
FAQs
How can I use "main question regarding" in a sentence?
You can use "main question regarding" to introduce a central inquiry related to a specific subject. For example, "The "main question regarding" the new policy is its long-term impact."
What are some alternatives to "main question regarding"?
Alternatives include "primary question concerning", "key question pertaining to", or "central issue concerning", depending on the context.
Is it always necessary to use "regarding" after "main question"?
While "regarding" is commonly used, you can also use alternatives like "concerning", "pertaining to", or "about" depending on the specific nuance you want to convey.
What is the difference between "main question regarding" and "key question regarding"?
The difference is subtle. "Main question regarding" refers to the principal question, while "key question regarding" emphasizes that the question is essential or crucial.
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Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
82%
Authority and reliability
4.1/5
Expert rating
Real-world application tested