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Casps are the main proteases activated during apoptotic signaling.
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Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.
Caspases are a family of cysteine proteases activated during apoptosis.
The fact that PAR-3 had no effect at all on inflammation suggests that PAR-4 is the main pathway by which proteases activate mouse platelets in vivo.
Cheng, Z. et al. Pathogen-secreted proteases activate a novel plant immune pathway.
Growing evidence demonstrates that coagulation proteases not only regulate hemostasis and thrombosis but also contribute to the many cellular responses via activation of protease activated receptors (PARs).
activated protein C. protease activated receptor.
Endogenous serine proteases, including tryptase and trypsin, cause itch by activation of the Protease activated receptor (PAR) family.
Vorapaxar is an antagonist of the protease activated receptor-1 (PAR-1), the principal platelet thrombin receptor.
Protease activated receptor 2 (PAR2) is an unusual G-protein coupled receptor in being self-activated, after pruning of the N-terminus by serine proteases like trypsin and tryptase.
Learning and memory deficits in mice lacking protease activated receptor-1.
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