Nevertheless, TLR seems to be the main pathway triggered by these compounds, and similar pathways may be triggered by actual microbes in infected tissues.
Activation of JAK kinases and subsequent stimulation of transcriptional activity of the STAT family of transcription factors is one of the main signaling pathways triggered by cytokines.
Two main pathways result in cochlear damage following noise exposure: mechanical damage [ 86] and biochemical pathways triggering apoptosis or necrosis.
In fact, Ca2+i signaling is the main intracellular pathway triggered by P2 receptors and we have shown its participation in the differentiation induced by ATP.
In this study, we analyzed the main survival and death pathways triggered by etoposide, a commonly used chemotherapeutic compound, in two MYCN-amplified and one non-amplified cell lines.
Bolland, S. & Ravetch, J. V. Inhibitory pathways triggered by ITIM-containing receptors.
The drugs activate at least one of the chemical pathways triggered by resveratrol, a substance that also showed increased endurance in mice.
Further, effector pathways triggered by class II antigens promote renal injury during rejection.
We investigated signaling pathways triggered by myelin in macrophages.
It was discovered as a regulator of the NRF2/KEAP1 pathway which is the main pathway responsible for triggering transcription of a battery of antioxidant and pro-survival genes in response to oxidative and electrophile stressors (Lo and Hannink 2008; Venugopal and Jaiswal 1996).
