Sentence examples for main pathways that from inspiring English sources

Metabolic flux analysis showed that the flux through the pentose phosphate (PP) pathway, one of the main pathways that produce NADPH, was reduced significantly in the recombinant strain when compared to that of the parent strain.

The technique involves restraining an animal in one small fitted cage and immersing it in 23 °C water to the xiphoid level (Ohta et al. 2009).The hypothalamic pituitary adrenal axis and the sympatho adrenal medullary systems are the main pathways that cause the release of corticosterone, noradrenaline and adrenaline (Pignatelli et al. 1998) and influence the composition of the microbiota.

The present review describes the main pathways that are modulated by TS-targeting anticancer drugs starting from the description of the normal functioning of the folate metabolic pathway, through the protein modulation occurring upon drug delivery to cultured tumor cells as well as cancer patients, finally describing how the pathways are modulated by drug resistance development.

This analysis reveals two main pathways that are likely involved in AD.

LPS synthesis is known to occur through three main pathways that lead to the synthesis of the O-PS, core oligosaccharide and lipid A [37].

The PI3K/Akt and mTOR/p70S6K pathways are main pathways that negatively regulate autophagy (Suh et al. 2007).

It was demonstrated that photoreaction of sarin was the main pathway that lead to the elimination of sarin vapor.

We next investigated the main pathway that is involved in ECM degradation: the matrix metalloproteinases (MMP) degrading pathway.

However, this is to our knowledge the main pathway that could mediate direct transfer of a membrane impermeable dye between eosinophils and epithelial/endothelial cells.

The HSPs (hereditary spastic paraplegias) are genetic conditions in which the main pathology is degeneration of the distal ends of the longest axons of the corticospinal tract, the main pathway that connects the motor cortex of the brain to the spinal cord [ 1– 4].

Considering that some studies have reported the function of FST in cell proliferation, we speculated that PI3K/Akt/mTOR signalling may be the main pathway that mediates signals from FST in myoblast proliferation.