Sentence examples for main pathways implicated from inspiring English sources

Candidate genes for CSC were selected based on their function from three main pathways implicated in CSC: stress response, steroid metabolism, and choroidal/endothelial permeability (Supp. Table S1).

TGF- β/bone morphogenetic protein (BMP /SMAD signaling is the main pathway implicated in EndoMT.

Among the main signalling pathways implicated in D/V patterning are sonic hedgehog (SHH), wingless (WNT) and the TGFβ-superfamily, mainly through the function of BMPs.

Two main molecular pathways implicated are Src/PI3-Kinase/Akt and Src/Ras/ERKs, which subsequently may activate NOS, as well as other enzymes (Alexaki et al. 2004; Cardona-Gómez et al. 2003; Guerra et al. 2004; Migliaccio et al. 2002; Viso-Leon et al. 2004).

The main purpose of this study was to direct attention to the fact that antagonistic pathways implicated in the aging process must be simultaneously targeted for optimal anti-aging effects.

A growing body of data on aberrant metabolic pathways implicated in cancer etiology now suggests that progressively accumulating mutations and epigenetic aberrations in genes encoding the main enzymes of specific metabolic pathways are prime contributors to oncogenic addiction in many cancers.

The exact pathways implicated in these processes need further investigation.

Alternate pathways implicated in tumor growth also exhibited upregulation such as VEGF signaling with 49 molecules.

Better understanding of post-translational modifications will allow more comprehensive mapping of networks and pathways implicated in certain diseases.

The chemokine receptors CCR2, CCR5, and CXCR3 are associated with pathways implicated previously in aneurysm pathogenesis.

9– 10 One of several physiological pathways implicated in increased intestinal permeability is the zonulin pathway.