Sentence examples for main pathways have from inspiring English sources

Again, both of these main pathways have been established from animal studies and the extent to which they apply to humans is still somewhat unclear.

Based on human and animal studies, four main pathways have been hypothesized to lead to PTB: 1) activation of maternal or fetal hypothalamic pituitary-adrenal axis, 2) inflammation and infection, 3) decidual hemorrhage, and 4) uterine distension [8].

Main pathways have been described for the production of miRNA, as well as other RNAs.

Three main pathways have been described: chromosomal instability (CIN), microsatellite instability (MSI), and CpG island methylation phenotype (CIMP; Boland and Goel 2010).

Two main pathways have been described to control Bim expression: ER stress, and the transcription factor FOXO3. p38MAPK can modulate both routes.

Two main pathways have a key role in the apoptotic program, namely, extrinsic and intrinsic apoptosis, which finally activate executioner caspases such as caspase-3, leading to characteristic features of this type of cell death, such as cell shrinkage, membrane blebbing, chromatin condensation, and DNA fragmentation.

Two main apoptosis pathways have been identified.

Four main genetic pathways have been described that control flowering in Arabidopsis: the photoperiod pathway (day lengths), the vernalization pathway (prolonged cold temperature experienced during winter), the gibberellin pathway (gibberellins) and the autonomous pathway (repression of FLC) [15], [16].

Three main resistance pathways have been identified for raltegravir, involving initial mutations of the N155, Q148, and Y143 residues within the integrase enzyme.

Although the main repair pathways have been identified and characterized using genetic, biochemical, biophysical, and cell biological approaches, we are still far from understanding the overall organization of DNA repair in cells.

In mammals, at least two main DSB repair pathways have evolved, namely non-homologous end joining (NHEJ) and homologous recombination (HR).