The main pathophysiological mechanisms of the development and progression of parenchymal changes in CVH are inflammatory cell infiltration, necrosis, fibrosis and decreased perfusion of liver parenchyma [10].
The main pathophysiological phenotype of SAKI is tubular damage.
The immune dysfunction is the main pathophysiological process in septic patients.
Figure 2 The main pathophysiological mechanisms involved in acute traumatic coagulopathy and transfusion strategy.
The clinical management of sepsis remains a difficult challenge, and pathophysiological advances have not yet been translated into effective therapeutic protocols [2].
The two main pathophysiological hallmarks of AD are the presence in the brain of extracellular amyloid plaques and of intracellular neurofibrillary tangles composed of hyperphosphorylated tau proteins.
The pathophysiology of EM is unfortunately unclear but local primary damage of vascular and neuronal structures has been proposed as the main pathophysiological mechanism underlying it.
Targeting main pathophysiological basis for treatment of HPS should be considered for future studies.
The main pathophysiological abnormality associated with increased levels of metabolic factors is visceral fat deposition.
Lipid peroxidation is a main pathophysiological result in various disorders [ 38].
