Sentence examples for main pathophysiological abnormality from inspiring English sources

The main pathophysiological abnormality associated with increased levels of metabolic factors is visceral fat deposition.

The inability to coordinate these anorectal processes underlies the main pathophysiological abnormality in patients with DD. 23 These patients are thought to have impaired rectal contraction, paradoxical anal contraction, impaired relaxation, or a combination of these mechanisms.

Shunt-induced hypoxemia is considered the primary pathophysiological abnormality and main diagnostic criteria of acute respiratory distress syndrome (ARDS).

This observation is relevant to the fact that women are considered more likely than men to have LV diastolic dysfunction as the main underlying pathophysiological abnormality of HF [ 48].

Although the pathogenesis of RP is poorly understood, current data points to three main pathophysiological mechanisms: vascular abnormalities, disturbances in the neural control of vascular tone and intravascular factors including circulating mediators and they influence on the balance between vasoconstriction and vasodilatation [ 2].

Treatment of the underlying pathophysiological abnormality seems logical, but the main pharmacotherapeutic options include acid suppression, prokinetic drugs, and antidepressants [ 6, 25- 27], all of which have limited effects.

The main pathophysiological phenotype of SAKI is tubular damage.

The immune dysfunction is the main pathophysiological process in septic patients.

Figure 2 The main pathophysiological mechanisms involved in acute traumatic coagulopathy and transfusion strategy.

The two main pathophysiological hallmarks of AD are the presence in the brain of extracellular amyloid plaques and of intracellular neurofibrillary tangles composed of hyperphosphorylated tau proteins.

The main pathophysiological mechanisms of the development and progression of parenchymal changes in CVH are inflammatory cell infiltration, necrosis, fibrosis and decreased perfusion of liver parenchyma [10].