Sentence examples for main pathogenic pathways from inspiring English sources

Candidates for this class of therapeutic agent are selected largely for their activities in other pathological conditions and our speculations as to other actions on what we suspect to be the main pathogenic pathways in DMD.

In this review, we discuss the main pathogenic pathways including proteolytic processing, nuclear shuttling and aggregation, mitochondrial dysfunction, and clearance of misfolded polyglutamine proteins and point out possible targets for treatment.

Although its etiology is not established, many pathogenic pathways are thought to contribute to tissue injury.

Actually, hsc70 protein acts as the main carrier of chaperone-mediated autophagy (CMA), a selective catabolic pathway for alpha-synuclein, the main pathogenic protein that accumulates in degenerating dopaminergic neurons in PD.

From this joint effort, major pathogenic pathways emerged.

Preeclampsia is a complex syndrome with variable phenotypes that suggest differing underlying pathogenic pathways.

Cellular senescence has evolved to restrict tumor progression but the accompanying senescence-associated secretory phenotype (SASP) promotes pathogenic pathways.

The improvement of the knowledge of these interrelationships should contribute to elucidate pathogenic pathways and design effective treatments for NAFLD.

In the present review, the main pathogenic bacteria that exist in treated sewage and biosolids are discussed.

It is crucial to explore this association and identify clinical subgroups in both epilepsy and headache patients sharing common pathogenic pathways and possibly common therapeutic targets.

The main pathogenic bacteria in this class is Mycoplasma (not to be confused with Mycobacteria).