Sentence examples for main pathogenic mechanisms from inspiring English sources

Autoimmunity is accepted as one of the main pathogenic mechanisms responsible for CCHD [ 10].

Chronic hyperglycemia and the corresponding glucotoxicity are the main pathogenic mechanisms of diabetes and its complications.

Because enhanced coagulation is one of the main pathogenic mechanisms in DVT, particular attention was paid to genetic variation in coagulation factor and anticoagulant genes.

According to a report from the 2007 International Dry Eye Workshop [ 2], the main pathogenic mechanisms of DEDs are tear film instability and hyperosmolarity.

Two main pathogenic mechanisms in GOR related cough have been described: micro-aspiration of gastric contents and a vagally-mediated oesophageal-tracheobronchial reflex [ 4].

Taken together, these findings strongly support a role for complement activation in the pathogenesis and progression of IgAN. Figure 1 summarizes the main pathogenic mechanisms involved in renal damage in IgAN.

VAP prevention targets the main pathogenic mechanism, which is bacterial translocation from stomach and oropharynx to the lower respiratory tract.

The main pathogenic mechanism of PAP is the insufficient clearance of the surfactant in the alveolar space, leading to its accumulation and consequent respiratory insufficiency [ 6].

Liver fibrosis is a feature in the majority of chronic liver diseases and oxidative stress is considered to be its main pathogenic mechanism.

The relation between antiphospholipid antibodies and CNS involvement in SLE, first reported in 1984, has now been confirmed; thrombosis associated with these antibodies is considered the main pathogenic mechanism [ 40- 43].

Endothelial dysfunction has been described as the main pathogenic mechanism responsible for CKD while weight loss and restoration of adipokine levels represent crucial factors to ameliorate the progression of renal diseases [ 94].