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Multidrug resistance (MDR) is one of the main obstacles of clinical chemotherapy.
One of the main obstacles of the diffusion of fuel cell electric vehicles (FCEV) is the refueling system.
This dedifferentiation process is one of the main obstacles of cartilage tissue engineering and could not be analyzed using the EB model system.
Despite the high number of advantages of membrane bioreactors (MBR), operational costs still remain as one of the main obstacles of this technology.
The recirculation of culture media at a speed of 1 μL/s provides nutrients and oxygen to the cultures at stable levels, which is one of the main obstacles of conventional two-dimensional (2D) PHH cultures15, 16, 20.
In addition, one of the main obstacles of modeling continuous mixing of particles is to know the appropriate values for the modeling parameters as well as validate modeling approaches.
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The main obstacle of the process is microalgae pretreatment and carbohydrates extraction from algal cell.
Restenosis after coronary interventions with stent implantation is still the main obstacle of interventional cardiology.
Moreover, the problem of photocatalyst separation which is the main obstacle of photocatalysis processes can be resolved by the photocatalytic membranes thereby advancing their practical application.
Since the main obstacle of the slags to be used as a construction materials is expansion of the matrix due to the free-CaO or free-MgO.
The main obstacle of the realization of SoC is the complexity of fabrication processes originated from the process differences between the transistors and the memories.
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