The main obstacle associated with miniaturization is the reduced surface area of electrodes for the accommodation of enzymes, leading to poor power output or detection signals.
Despite these advantages of the passive targeting, the main obstacle encountered with the clinical use of the PEGylated CS-NPs is how to facilitate their internalization in the target cells while reducing the unintended side effects.
The main obstacle associated with αβ TCR transfer, however, is that γδ T cells usually do not express CD4 or CD8 co-receptors required for the efficient recognition of peptide-MHC.
The low electrochemical reactivity of ZnO is the main obstacle that interferes with building an electrochemically rechargeable Zn air battery.
Both computer architects and circuit designers intent to reduce power and energy (without a performance degradation) at all design levels, as it is currently the main obstacle to continue with further scaling according to Moore's law.
So far, House Democrats have emerged as the main obstacle, as Republicans, with the aid of some Democrats, try to pass a bill giving Obama special authority to expedite international trade deals through Congress.
(Payatas Medical Outreach) The main obstacle was communication with the local NGO.
The main obstacle was communication with the local NGO.
The midwives themselves and their own personal barriers may be the main obstacle to working with this delicate matter, and therefore it is necessary to provide carefully designed educational programs to all clinically active midwives [ 18].
Only the Shouldn'ts contain those who may never agree with the idea, but despite all the many potential objections to UBI, the team concluded the main obstacle is public unfamiliarity with the existence of the idea itself, and that if the idea can be introduced with sensitivity to the diversity of American interest groups, it will fare well, and we can win.
