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Because ecological study has some main limitations including ecological fallacy and difficult control of some confounding factors etc.
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the main limitations include a higher graft failure rate, delayed immune reconstitution after transplantation with high rates of life-threatening infections, a higher incidence of post-transplant lymphoproliferative disease (PTLPD), and severe acute and chronic graft-versus-host disease (GVHD).
Main limitations include the cross-sectional assessment and the lack of objective measures of biological rhythms in relation to QOL.
Its main limitations include the lack of three-dimensional (3D) data reconstruction and visualisation of the surrounding cardiac structures, both of which are overcome with cross-sectional imaging techniques, including CCT and CMR.
The main limitations include the tedious process required to collect the gene lists and the potential for publication bias.
This study's main limitations include those inherently associated with open-label trials, such as potential bias, which can, for example, lead to greater withdrawal of consent in 1 treatment arm.
The main limitations include the small number of studies with relatively small sample sizes comparing different antenatal magnesium sulphate regimens, and the missing data for several important outcomes in almost all trials.
Despite inevitable coding errors in clinical practice, the estimated predictive value of a diagnosis of pneumonia in Denmark is 90%. 3 The main limitations include potential un- and undermeasured confounding, lack of history of marital status, and misclassification.
Although the findings from this study are encouraging, the main limitations included fewer cases in re-audit than in the initial audit; this was the result of new eclampsia units opened in the three municipal hospitals that are the main referring hospital.
The main limitation includes an inherent limitation as a retrospective study.
The main limitation includes the non-random selection of physicians who have attended two national conferences; and the low sample size when considering medical specialties sub-groups.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com