Sentence examples for main isoforms are from inspiring English sources

The main isoforms are RhoA and Rac1.

The two main isoforms are targeted to the nucleus and cytoplasm (ncOGT) and the mitochondrion (mOGT) (Hanover et al. 2003; Love et al. 2003).

Wang et al. reported that CEACAM1-4S is the predominant isoform in NSCLC tissues, whereas in normal lung tissues the main isoform is CEACAM1-4L [ 49].

RORγ has two isoforms: the main isoform is expressed in adipose tissue, liver, muscle and kidney, whereas expression of RORγt is restricted to immune cells.

The pI for the main isoform was 8.69 ± 0.00 for Trastuzumab-Probiomed and 8.70 ± 0.01 for the reference product (Table 1) which is consistent with the expected pI variations, no larger than 0.2 units, to establish the identity of mAb.

Two other SLC1A2 N-terminal non-synonymous variants in the main isoform were also detected in this study; case-only variant rs199599866 G>A (p. (R31Q)) was detected in one BD case and one SZ case; and ss825678893 C>T (p. (A7V)) was detected in one BD case and one control subject.

On the other hand, charge heterogeneity evaluated through cIEF analysis revealed that isoelectric points (pI) for the main isoform were 8.69 ± 0.00 (CI 95%) for Trastuzumab-Probiomed and 8.70 ± 0.01 (CI 95%) for the reference product, in accordance with the expected pI variations during manufacturing, no larger than 0.2 units [ 15, 16].

Due to the structural and charge differences in their very C-terminus, the two main merlin isoforms are likely to have different binding partners in cases where the C-terminus is necessary for protein-protein interactions.

However, the full-length and the Δ2 variant are the main isoforms and are equally expressed in resting human nTreg cells [ 10].

Raw spectra covering elution of the four main TTR isoforms were summarized and subsequently deconvoluted (i.e. decharged and deisotoped) by the Xtract algorithm within Qual Browser (Xcalibur ver. 2.0.7, Thermo Scientific) using the three most intense charge envelopes as described earlier [ 20].

The two main differences between these isoforms are that (i) N-Ras is mostly targeted to the Golgi and H-Ras is localized mostly to the PM and that (ii) H-Ras has two palmitoyl modifications while N-Ras has only one.