Sentence examples for main isoform is from inspiring English sources

Wang et al. reported that CEACAM1-4S is the predominant isoform in NSCLC tissues, whereas in normal lung tissues the main isoform is CEACAM1-4L [ 49].

RORγ has two isoforms: the main isoform is expressed in adipose tissue, liver, muscle and kidney, whereas expression of RORγt is restricted to immune cells.

The pI for the main isoform was 8.69 ± 0.00 for Trastuzumab-Probiomed and 8.70 ± 0.01 for the reference product (Table 1) which is consistent with the expected pI variations, no larger than 0.2 units, to establish the identity of mAb.

Two other SLC1A2 N-terminal non-synonymous variants in the main isoform were also detected in this study; case-only variant rs199599866 G>A (p. (R31Q)) was detected in one BD case and one SZ case; and ss825678893 C>T (p. (A7V)) was detected in one BD case and one control subject.

On the other hand, charge heterogeneity evaluated through cIEF analysis revealed that isoelectric points (pI) for the main isoform were 8.69 ± 0.00 (CI 95%) for Trastuzumab-Probiomed and 8.70 ± 0.01 (CI 95%) for the reference product, in accordance with the expected pI variations during manufacturing, no larger than 0.2 units [ 15, 16].

The main isoforms are RhoA and Rac1.

The two main isoforms are targeted to the nucleus and cytoplasm (ncOGT) and the mitochondrion (mOGT) (Hanover et al. 2003; Love et al. 2003).

The expression of SCD1, the main SCD isoform, is increased in several human cancers, chemically induced tumors, as well as in oncogene-transformed cells [1], [13], [15] [18].

53 A more recent study has shown that in filaggrin-deficient ft/ft mice, sPLA2-IIA is upregulated along with NHE1 expression, while sPLA2 forms -IIF and -X do not, 1 contrasting with a previous study that demonstrated that sPLA2-IIA does not contribute to acidification and barrier function and sPLA2s-X is the main isoform to be secreted from keratinocytes.

The main charge isoform was obtained at a purity and yield larger than 90%.

The isoelectric point (pI) of its charge variants ranges from 8.0 to 8.9, whereas the main isoform pI is 8.7.