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No main intervention effect was found on feedforward activation levels and reflex amplitudes underlining the absence of changes in the way patients with LBP reacted across perturbation conditions.
Despite between paradigm differences in the logic of inquiry there is a shared understanding on the need to provide context-relevant explanatory evidence beyond the main intervention effect.
The main intervention effect will be assessed on the basis of a Cox-regression analysis between exercisers and controls (relaxation group) as defined at randomization, regardless of exercise adherence, i.e. according to the intent-to-treat principle.
The main intervention effect will be assessed on the basis of a comparison between exercisers and controls as defined at randomization, regardless of exercise adherence, i.e., according to intent-to-treat principle.
The main intervention effect will be assessed on the basis of a comparison between exercisers and controls as defined at randomization, regardless of exercise adherence, i.e. according to the intent-to-treat principle.
Assuming the effect size to be the same for both branching and feedback interventions, a sample size of 88 students would provide sufficient power to detect the main effects and an interaction effect that was twice as large as the assumed main intervention effect in the setting shown in Table 2.
Similar(54)
We evaluated the main intervention effects in multilevel logistic regression models including patient and general practitioner variables, comparing post-intervention data for the intervention and the control arms.
Aside from the lack of main intervention effects, there were significant interactions between socio-economic status and parent FV consumption (F1, 47 = 5.51, p =.023).
Mixed-model analysis on difference scores (T2 minus T1) revealed there were no significant main intervention effects for girl BMI z-scores (F1, 5 = 0.42, p =.544); or Parent BMI (F1, 5 = 1.58, p =.264).
Given unforeseen recruitment problems and some loss to follow-up, a target of 112 students should be easily achievable to quantify the main intervention effects (branching and feedback) which are the primary focus of the study, with increasing recruitment above this target providing increasing power to detect potential interactions between the main effects.
The statistical significance of the main intervention effects was assessed using a multiple, random effects logistic regression model, adjusting for the other intervention and five covariates (age, gender, GP's practice, previous invitation, inclusion or not of a GP's signature) (Green et al, 2002; McAlister et al, 2003; Montgomery et al, 2003).
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