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After World War II the European population gradually increased by migration, but the main influx of white and Polynesian settlers occurred in the years leading up to and including the nickel boom of 1969 72.
Initially, the main influx was composed of Arab and Western technical, professional and administrative personnel, but subsequently substantial numbers came from Southeast Asia.
The main influx transporters for (anti folates are the recently identified proton-coupled folate transporter (PCFT), expressed predominantly in the small intestine and in several solid tumors; and the ubiquitously expressed reduced folate carrier (RFC).
In contrast, typical MHC II- monocytes, mainly of the CD4- subset, did not increase until 12 to 14 days after cell transfer, coinciding with the main influx of polymorphonuclear cells.
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We next tested whether voltage-operated channels, which are believed to represent the main Ca2+ influx pathway in the cone IS [2], [5], [12] contribute to baseline [Ca2+]i.
CRAC channels are composed of the ORAI1 pore protein and two activating molecules, stromal interaction molecule (STIM) 1 and 2. SOCE mediated by ORAI1, STIM1 and STIM2 is the main Ca2+ influx pathway in T lymphocytes.
This co-ordinated and potent mechanism, with opposite effects on the main Cl− influx and Cl− efflux mediators involved in cellular Cl− homoeostasis, is of obvious interest for drug development.
"One of the main reasons behind the influx of technical jobs is the School District of Pickens County's emphasis on Science, Technology, Engineering and Mathematics.
Channel permeations and apoplastic are the main pathways of Na+ influx under salt tress.
In smooth muscle, CaV1 are the main responsible to Ca2+ influx.
"The main reason is the influx of IDP families from areas where there is trouble to relatively safer locations".
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