Sentence examples for main haplotypes were from inspiring English sources

Two main haplotypes were shared by 91.5% of moths sampled.

Three main haplotypes were identified: ACCG, ATCA, and GCGG (SNP order: rs6269, rs4633, rs4818, rs4680) and correspond to the low, intermediate, and high enzyme activities of COMT, respectively, identified by Nackley and colleagues[33].

Three main haplotypes were identified GCGG, ATCA, and ACCG and functional analysis in a mammalian expression system revealed changes in enzyme activity ranging from a decrease of 2.5 3 fold with the intermediate haplotype, ATCA, to a decrease of 18 25 fold with the low activity haplotype, ACCG[33].

Two main haplotypes were found and are shown in Figure 2. Two distinct haplotypes in Caucasians contain the following alleles.

There was no relationship between haplotype distribution and the cytogenetic status of the cell lines, which was studied in detail by Roschke et al (2003) and is freely available on the NCBI site (http://www.ncbi.nlm.nih.gov/sky/skyweb/cgi): the three main haplotypes were present in cells which were diploid, polyploid or aneuploid for chromosome 20, and so were also the rare haplotypes.

Since the main haplotype was used instead of the original sequence, other methods should be applied to clarify the selection of this protein.

We report here that DILI caused by at least nine different drugs can be related to two main haplotypes, which are illustrated in Figure 2. Interestingly, for ticlopidine-induced DILI in Japanese patients the strongest association has been detected with A*33 03, which has higher frequency in Asian populations than in Caucasians.

If the shared haplotypes were the main source of the high correlation found between recombination and genetic distance, we expect to observe this correlation also in the simulated data.

The network topology of this MSN showed that most of the minor haplotypes were closely connected to the three main ones which suggested that they could be variants around the main haplotypes.

The haplotypes were further categorized according to the classification used in our previous study into two main families (Fig. 1B).

The main effect of haplotype group was fitted as a fixed class factor in the abovementioned ASREML analysis to determine which haplotypes were associated with the desirable phenotypes of VL and WG.