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SGCs are the main glial cells in DRG, and they become activated and proliferate after nerve injury or inflammation [ 10].
Now, we published in Cell Death and Discovery that the Hippo/YAP intracellular signaling pathway has an important role in regulating some biological processes in the main glial cells of the peripheral nervous system, the Schwann cells (SC), see Figure 1.
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In the vertebrate central nervous system (CNS), two main glial cell types can be identified: oligodendrocytes and astrocytes.
However, to date, no information is available concerning the expression of MCTs in tanycytes, the main glial cell present in the AN [28], [29], [30].
Neurons from the VMH are in close contact with highly elongated ependymal cells known as tanycytes [26], [27], which are the main glial cell present in the basal hypothalamus[28], [29], [30].
Peripheral nerves consist of bundles of axons, with each axon associated and enveloped by Schwann cells (SCs), the main glial cell of the PNS.
In summary, Lee et al. report that oligodendroglia, the main myelinating glial cell type of the CNS, metabolically support axons via the lactate transporter MCT1 (Lee et al., 2012).
The trigeminal ganglion (TG) contains three main cell types: neurons, satellite glial cells (SGC) and Schwann cells; the first two have before been studied in vitro separately.
Alternatively, hair follicle stem cells (HFSCs, that have not been artificially induced to increase potency) of adults have the potential to differentiate into cell types of all three embryonic germ layers, including nerve and glial cells (the main components of the brain, reviewed in 37).
Generally, the neurons and glial cells are the main cell types in the CNS.
In this study we show that radial glial cells are the main source of new cells in the regenerating radial nerve cord in these animals.
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