Sentence examples for main functional phenotypes from inspiring English sources

Despite their intermediate activation state, macrophages are generally classified into two main functional phenotypes, reflecting the Th1/Th2 response of CD4 T helper cells [ 18– 20].

We used Mb as the model protein because its main functional phenotype (i.e., O2-binding as measured by the O2 pressure at half Mb saturation [P50]) is almost constant in mammals (Dasmeh and Kepp 2012), which is also reflected in the conservation of the important functional residues (Suzuki and Imai 1998; Scott et al. 2000).

Finally, we utilized the GOLDN population to explore (i) whether age is associated with APOE methylation, (ii) whether the effects of age on APOE methylation leads to changes in plasma lipids, the main functional phenotype of APOE, and (iii) whether the effect of age on APOE methylation can be modulated by methylation-related genetic variants in the APOE locus.

Simultaneous measurement of IFN-γ and IL-2 at the single cell level identifies T cell cytokine profiles which reflect their memory phenotype and defines three main functional T cell subsets: effector cells that mainly secrete IFN-γ only, effector-memory cells primarily secreting both IFN-γ and IL-2, and central memory cells secreting only IL-2 [4].

These cross-category comparisons provide a tentative link between the evolutionary history and functional phenotypes of our isolates where the two main branches of the core and pan-genome phylogenies may represent adaptive paths leading toward distinctive ecological properties.

Because the proteins are the main functional molecules in the cells, their levels reflect much more accurately the cellular phenotype and the regulatory processes within them than gene levels, mutations, and even mRNA levels.

Macrophages are highly plastic cells that adopt different functional phenotypes in response to environmental signals.

There are, in reality, many different modes of activation, resulting in an array of macrophage functional phenotypes [8].

The modules are grouped in three main functional blocks.

Figure 4 Main functional components of the vehicle infrastructure.

The main functional module realization is described as follows.