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However, a ∼50° rigid kink occurs as an adaptation in the three helical bundle of the T. brucei receptor, and we propose that it has two main functional consequences.
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The main functional consequence of this nucleotide addition is to protect newly transcribed mRNAs from degradation.
As a consequence, compression of the coronary artery lumen in systole, extending into diastole, is the main functional consequence of this anatomic abnormality.
While these studies have provided vast insight into the epigenetic mechanisms that can silence E-cadherin and their functional consequences, they also indicated that E-cadherin inactivation through transcriptional repressors is not the main driver of ILC development.
Throughout the years, the main therapeutic target is the control of disease activity as soon as possible to prevent structural damage and functional consequences.
In this area, the main challenge is to perform analytical and simulation studies which can identify and characterize their composite effects, and investigate their functional consequences.
Of special interest are features that may have functional consequences.
Here, we review these advancements and highlight their functional consequences.
Subsequently, the functional consequences of such phosphorylation were examined.
The functional consequences of these structural changes remain uncertain.
Functional consequences of integrin-linked kinase activation in podocyte damage.
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