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The main finding presented here is that activin A regulated cell behavior by antagonizing BMPs that signal through ACVR2A/ACVR2B/ALK2.
The main finding presented here is that very low intensity AC current delivered in the proximity of malignant tumors can reduce drug resistance by a mechanism implicating impaired translocation of MDR1 to its functional localization at the plasma membrane.
The main finding presented in our study is that the contralateral dorsal posterior insula (dpIns) was the only region that was observed to track pain intensity; one of the many fundamental variables that are integrated by a number of other key brain regions into a complete tonic pain experience.
A main finding presented by Hughes and colleagues was that people with HIV had significantly more limitations across all the five health dimensions of the EQ-5D instrument [ 10], while Jelsma et al. found that antiretroviral treatment improved along all five dimensions, but especially for pain/discomfort [ 11].
The main finding presented in this article is that the positive and significant relationship between human resources and health outcomes can be extended to a much broader measure of population health (i.e. DALYs), and that this relationship may follow different patterns according to the different groups of diseases.
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Table 25 summarizes the main findings presented in this paper.
However, all of our main findings (presented in Figures 1 and 2) and half of the interaction models would pass Bonferroni correction for multiple testing.
Reviewer 2 notes that one of the main findings presented is that Hairy interacts with many "off target" sites, with relatively few linked to transcriptional function.
While all the main findings presented in Table 2 were also found in the postmenopausal group, which was also larger in size, some of the correlations were lost in the premenopausal group.
A post hoc sensitivity analysis of the primary endpoints restricted to valid data from the first session only, and consequently not affected by carry-over, showed similar results to the main findings presented in table 1.
However, there are two main findings present in all PPS studied (PKAN, PLA2G6-associated neurodegeneration – PLAN, neuroferittinopathy, mitochondrial membrane protein-associated neurodegeneration – MPAN): iron-laden pigmentation and spheroids with a predilection for pallidal involvement in PKAN [ 31, 32 ▪] but a wider lesion distribution in the remaining syndromes [ 33, 34▪▪, 35 ▪].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com