Sentence examples for main enzyme that from inspiring English sources

In active SLE T cells, the expression of DNA methyltransferase 1 (DNMT1), the main enzyme that maintains DNA methylation during cell division, is reduced [9], and the promoter sequences of the aforementioned methylation-sensitive genes are hypomethylated [2], [6].

Interestingly, although CBS is thought to be the main enzyme that produces hydrogen sulfide in the mammalian brain [ 45], we did not observe a GFP signal in neurons.

For example, human pancreatic lipase as shown in Figure 4, which is the main enzyme that breaks down dietary fats in the human digestive system, converts triglyceride substrates found in ingested oils to monoglycerides and two fatty acids.

LRAT is the main enzyme that catalyzes retinyl ester formation in most tissues, with the exception being adipocytes that instead exhibit acyl-CoA-dependent transferase activity of a protein (acyl-CoA:retinol acyltransferase or ARAT) yet to be identified.

mTOR (mechanistic or mammalian target of rapamycin) is the main enzyme that performs intermediate control of the signaling pathway through a phosphotransfer process.

MMP1 is the main enzyme that degrades collagen I and collagen III in scars [ 12].

Activated checkpoint kinase 2 (Chk2) is a tumor suppressor as one of the main enzymes that affect the cell cycle.

Xylanases (endo-β-1,4-xylanase; EC 3.2.1.8) are the main enzymes that cleave the β-1,4-glycosidic bonds in the xylan backbone.

Chitinase, β-N-acetylglucosaminidase and chitin deacetylase are three main enzymes that involved in chitin degradation, while four critical enzymes, trehalase, hexokinase, glucose-6-phosphate isomerase and glutamine and fructose-6-phosphate aminotransferase, are needed for the de novo synthesis of chitin (KEGG pathway map: ko00520).

The formation of 1,25(OH)2D3, the biologically most active natural ligand of the VDR, is mediated through several main enzymes that facilitate hydroxylations of vitamin D at position 25 in the liver (CYP2R1, CYP27A1) and of resulting 25(OH)D3 at position 1 in the kidneys (CYP27B1).,, These hydroxylases belong to a class of cytochrome P450 mixed function monooxidases.

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases are the main enzymes that produce oxidative stress, which plays an important role in painful diabetic neuropathy.