The Per-Protocol dataset was used as the primary analysis set for the primary endpoint analysis.
A composite primary endpoint analysis was performed (cf. Fig. 5).
The main endpoint of the present analysis was the proportion of patients with AKI defined on Kidney Disease Improving Global Outcomes (KDIGO) criteria at the 48th hour.
An analysis of the study's main endpoint was performed for these patients, and any analysis of secondary endpoints would not have enough statistical power, Home says.
Main endpoints for the analysis were response, response duration, progression-free survival (PFS), overall survival (OS) and toxicity.
Two patients (one in each group) were excluded from the analysis on the main endpoint because of inadequate location of the laser-Doppler probe, and two patients (one in each group) could not be investigated at T3 because of the need for prompt surgical management to control the source of sepsis.
In this analysis, we use the serum HBV DNA level as the main endpoint for the various rescue strategies and for estimation of the risk of cirrhosis and hepatocellular carcinoma.
The main endpoint was hospital mortality.
The main endpoint was the rate of NIV failure.
The main endpoint of ICU resuscitation was lactate normalization.
