Sentence examples for main effectors of from inspiring English sources

Natural killer (NK) cells, the main effectors of the innate immune system, recognize and clear targets using different mechanisms than CD8+ T cells, offering an alternative or complementary approach for HIV clearance strategies.

As the main effectors of dermal remodelling produced by cells (extracellular proteases) generally have low substrate specificity, we recently suggested that the differential susceptibility of key extracellular matrix proteins to the processes of photoageing may be due to direct, as opposed to cell-mediated, photodamage.

Microglial cells are the main effectors of the innate response after CNS injuries.

Rho-kinase (ROCK) and the formin protein mDia1 are the main effectors of Rho [16] [18].

Protein synthesis is a fundamental cell process and ribosomes - particularly through the ribosomal RNA that display ribozyme activity - are the main effectors of this process.

The main effectors of plasticity of the bulbar network are thought to be the inhibitory granule cells which regulate output of the olfactory message through reciprocal synapses with the mitral cells [20].

Activation of Yorkie, the main effector of hippo signalling, drives proliferation of glial cells33.

In mammals, the Yorkie homologue Yes-associated protein 1 (YAP1) represents the main effector of the hippo pathway and exerts its effects by forming nuclear complexes with co-activators of the TEAD family22,23.

Objective: There is evidence that angiotensin II, the main effector of renin-angiotensin system, plays a crucial role in the pathogenesis of chronic renal injury.

The main effector of this system is angiotensin II (Ang-II), which derives from the proteolytic cleavage of angiotensin I (Ang-I) by angiotensin converting enzyme (ACE).

However, it is unlikely that CCR7 is the main effector of TLX1-induced oncogenesis.