Sentence examples for main effector mechanisms from inspiring English sources

The main effector mechanisms of complement activation are induction of inflammatory response and phagocytosis and cell lysis.

The key finding of this study is that autoantibody-mediated arthritis in K/BxN mice can occur via a C5 activation pathway that requires neither C3 nor activating FcγRs, the two main effector mechanisms of IgG molecules.

The main effector mechanism of CD4+ T cells assumed in this model was IFN-g-mediated TRP starvation of chlamydial RBs.

Fas ligand (FasL) is expressed by natural killer cells and cytotoxic T lymphocytes (CTLs, i.e. CD8+ effector T-cells) and Fas FasL interaction is the main effector mechanism of CTLs inducing apoptosis of virus infected hepatocytes [ 5, 6].

Antibody-dependent cellular cytotoxicity is suggested to be the main effector mechanism of WX-G250 (Surfus et al, 1996) and is mediated by the interaction between the Fc region of an antibody bound to a tumour cell and the Fc γ receptors on immune effector cells, such as neutrophils, macrophages and NK cells (Clynes et al, 2000).

Fc-dependent complement-mediated antibody responses are one of the main humoral immune effector mechanisms against flaviviruses, and virus opsonization is a major mechanism of viral clearance that operates via complement receptors [2].

Advanced undergraduate students and postgraduates with a grasp of the main groups of leukocytes and immune effector mechanisms, as well as specialists in other subdisciplines, will find this textbook to be a highly useful and readable introduction to the immune system's mainstay, the battle against infection.

The appealing concept to ameliorate disease by abrogating autoantibody production and thereby reducing autoantibody-dependent effector mechanisms has served as the main rationale for the use of B-cell-directed therapies in patients with SLE in addition to the inhibition of B-cell-mediated processes such as antigen presentation, cytokine production and activation of T cells.

CD11b+Gr-1+ cells inhibit antigen-activated T cells through a cognate-independent mechanism that involves arginase and nitric oxide synthase as the main effector pathways [ 60].

This confirms previous results showing that oatA is not the main effector of E. faecalis lysozyme resistance [27], and that dltA is also involved in this mechanism.

(6) H2S acts upon effector mechanisms known to mediate hypoxic responses.