Sentence examples for main effect when from inspiring English sources

These models had no main effect when the allele frequencies of the functional SNPs was 0.5.

We have shown that the power to replicate a main effect when the true underlying model is complex depends on the allele frequencies at interacting loci in the replication sample.

This highlights that the change in allele frequency required to prevent replication of a main effect when an underlying epistatic model is responsible is highly dependent on that model.

It is evident that large differences in allele frequency at one interacting locus affect the power to detect the main effect of another locus; however we demonstrate that even small differences in allele frequency at an interacting locus negatively impacts a study's power to replicate a true main effect when the full genetic model is epistatic.

However, the present study did not reveal a significant main effect when prosody is manipulated (Table 1: main effect [ME] segmental).

We stated in the Methods section that Equation (1) could be used to test the second locus main effect when its genotype frequency distribution is known, and Supplementary Material Table S7 gives a confirmation of this statement.

The minimum breakdown designs provide the highest probability to derive a non-singular residual design for estimating the grand mean and all the main effects, when a fraction of experimental data is unavailable.

To examine the effects of allele frequency on replication of main effects when there is an underlying complex disease æ tiology we first generated genetic models.

For instance, in case f (Figure 1f) interactions occur in the absence of main effects when allele frequencies are equal (0.5), but marginal effects arise and can be picked up in one-dimensional genome scans when allele frequencies are different.

In this case, the interaction effects show up as allelic main effects when the environment is dichotomous.

Misclassification of exposure generally leads to attenuation of the main effects when the error is non-differential [ 51].