The statistical analysis revealed that all main effects influenced the surface roughness.
As such, it defined the main effects influencing dissolution performance of the tested batches, which is an important and often difficult step in research and development (R&D) and is a basic prerequisite for further dissolution method optimization, performed according to the characteristics of the given API and its formulation.
This is understandable, given that the environmental main effect only influences the phenotypic means of the genotypic groups, but not the differences in phenotypic means between the genotypic groups.
The main effects and influences of the 2-factor interactions of these parameters on the performances of the EDM process with the bundled electrode are discussed.
The repeated measures 2 × 2 factorial ANOVA found no main effect of human influence, F 1, 17) = 0.06, P = 0.81; no main effect of dog influence, F 1, 17) = 0.01, P = 0.93; and no interactions between human influence and dog influence, F 1, 17) = 0.01, P = 0.94.
Theoretically, all main effects could influence each other.
Whilst the effects of measurement error on estimation procedures such as linear regression are well known for main effects, the influence of errors on estimation of interaction terms is not well documented.
However, Jannink recently identified QTLs by analyzing genetic background interactions in association studies, and was able to detect loci that have no main effect but which influence a trait only through their interactions with other loci.
Its main effect is through its influence on consumer confidence, which Greenspan does care about.
Smoking and illicit drug use were not included in the model because few women reported these behaviors and they did not influence main effect estimates.
