Sentence examples for main downstream insulin from inspiring English sources

In the offspring of high fat fed ewes Akt phosphorylation (the main downstream insulin signalling pathway) and insulin receptor mRNA expression were reduced [ 64].

This was explained by the activating effect of adiponectin on intracellular insulin signaling through phosphorylation of IRS-1 and the serine/threonine protein kinase (Akt), the main downstream molecules of insulin.

If short sleep duration is responsible for disruption in cortisol levels (that is, elevated evening and night-time cortisol levels) then this may, over time, adversely affect carbohydrate metabolism60, 61 decreasing insulin sensitivity and downstream insulin signaling.

Downstream insulin signaling was assessed by determining basal and insulin-stimulated Erk and Akt phosphorylation in differentiated adipocytes.

In details, we studied i) insulin-induced IR activation in all three cell types, ii) downstream insulin signaling and subsequent insulin action on glucose metabolism in liver- and skeletal muscle-cells and iii) beta-cells insulin secretion and survival.

Akt/PKB is associated with a downstream insulin signaling, and PKCβ attenuates insulin-stimulated Akt phosphorylation.

In the db/db diabetic mouse model, intranasal insulin reduces brain atrophy, improves memory, and increases downstream insulin signaling molecules.

For example, how does Dmp53 regulate dILP2 expression to effect downstream insulin signaling pathway effects?

One of the main downstream targets of COUP-TFII is the angiogenic factor Angiopoietin-1.

Oxidative stress caused by NPs is reported to be the main downstream events of the inflammation.

PI-3K activates Akt one of the main downstream kinases in different cells [ 26].