Sentence examples for main downstream effect from inspiring English sources

These results suggest that these compounds have a common effect on cellular physiology and that the main downstream effect of CGs is protein synthesis inhibition.

The main downstream effect of AMPK activation is the inhibition of mTOR signaling pathways [ 13, 14].

Interestingly, inhibition of the MAPK pathway by PD0325901 as well as knockdown of p65 (RELA), the main downstream effector of NF-κB signaling, had only minimal effects on the level of NOXA mRNA or even enhanced NOXA transcription.

One of the many downstream effects of climate change is ocean acidification.

As selective EGFR inhibitor AG 1478 blocked G3 effects on tumor cell migration while MEK inhibitor PD 98059 did not suggest that ERK was the main downstream signaling component when specifically considering effects on cell migration.

These cellular effects were paralleled by decreased Akt phosphorylation, the main downstream target of PI3K.

As startup fuel prices go down, the downstream effect is powerful: starting and scaling companies has gotten yet even cheaper.

This was probably related to a downstream effect of deoxyHb.

This was explained by the activating effect of adiponectin on intracellular insulin signaling through phosphorylation of IRS-1 and the serine/threonine protein kinase (Akt), the main downstream molecules of insulin.

Minnich acknowledged to Capital & Main that getting members to quit the union has "downstream effects" that "impact the dollars that the union has," but that his group's primary goal is to let union members know they have the right to leave the union.

Nevertheless, retinoic acid and its analogs are also involved in the inhibition of AP-1 transcription factors (Section 3.4.2.2 Prolonged downstream effects of ASK1 activation), which constitute the main dimerization partners for NRF2.