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The main diseases causing admission to intensive care were: lung problems in 34 (65%), early sepsis in 9 (17%), and hypoxic-ischemic encephalopathy in three (6%).
The awareness of shepherds regarding brucellosis was investigated through the use of open questions concerning the main diseases causing abortion in sheep, whether or not these diseases affect humans, the main signs of the disease and potential routes of transmission to humans.
In this study, we have documented that the majority of parents/caretakers in two districts in rural Uganda take their febrile children to the private sector and that the care that they receive at drug shops for treatment of the main diseases causing pediatric death is inadequate.
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Both toxins as the main disease-causing contributors are exploited as antigens in the vaccine development against tetanus and diphtheria (Alpar et al., 2001).
The main disease cause was defined according to the Global Burden of Disease GBDD) study classification [ 3, 4].
Following the success of Haemophilus influenzae type b and pneumococcal conjugate vaccines, Nm vaccines coupling a carrier protein to the main disease-causing polysaccharide serogroups were developed.
The following epidemic season NmW ST-11 was the main disease-causing genotype and by the end of 2012, this clone dominated among carriage strains and with the highest prevalence found in Dandé.
Additionally, rs33980500 has recently been reported to encode a mutant protein with an almost completely disrupted binding property to TRAF6, supporting its impact as a main disease-causing variant and modulator of IL-17 signaling [ 3].
For each article, multiple variables were recorded such as: year and journal of publication, type of study, health intervention targetted, perspective of analysis, type of costs and sources of information, first author's affiliation, explicit recommendations aimed at decision-making, and the main disease cause to which the intervention was addressed.
The risk allele of p.Asp10Asn (rs33980500) proved to be most significantly associated and to encode a mutant protein with an almost completely disrupted binding property to TRAF6, supporting its impact as a main disease-causing variant and modulator of IL-17 signaling.
Secondary objectives were to explain differences in diagnostic predictive value between the two scores and to assess DIC and its evolution of DIC according to the main obstetrics diseases causing ICU admission.
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